Description
CINP, also known as Cyclin-dependent kinase 2-interacting protein, belongs to the CINP family. This protein interacts with the components of the replication complex and 2 kinases, CDK2 and CDC7, thereby providing a functional and physical link between CDK2 and CDC7 during firing of the origins of replication. Recombinant human CINP protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography